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Opioid prescribing too high after minimally invasive surgery

August 19, 2019 | Anesthesiology News

Opioid prescribing after minimally invasive surgery (MIS) remains unacceptably high, according to research conducted at the University of California, San Francisco (UCSF). Of nearly 400 MIS patients surveyed, 90% said they were prescribed opioids after surgery, and 13% of these patients asked for a refill as late as three months after the procedure. The study, which was presented at the 2019 annual meeting of the American Society of Regional Anesthesia and Pain Medicine (abstract 7353), demonstrates that despite efforts to tackle opioid prescribing, it remains a problem and can lead to significant hazards for patients. Solmaz Manuel, MD, an assistant clinical professor in the Department of Anesthesiology and Perioperative Care at UCSF, and her colleagues asked 393 adult patients who underwent ambulatory MIS at UCSF over an eight-month period whether they were prescribed opioids for postoperative pain control and whether they were taking them. The most common procedures were hysterectomy, myomectomy, salpingectomy, oophorectomy, diagnostic laparoscopy, hernia repair and cholecystectomy.

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Disappointment for Australian innovation

July 23, 2019 | BiotechDispatch

Novartis has quietly scrapped further development of olodanrigan for neuropathic pain. The Swiss company acquired the investigational therapy, also known as EMA401, through its US$200 million acquisition of Spinifex Pharmaceuticals in 2015.

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America on opioids: 76B pills

July 18, 2019 | LinkedIn

Ten of America's largest drug companies are responsible for releasing 76 billion oxycodone and hydrocodone pain pills from 2006 through 2012, according to previously unreleased data obtained by The Washington Post. These companies, including Walgreens, CVS and Walmart, are being sued in federal court by nearly 2,000 cities, towns and counties claiming they plotted to "flood [America] with opioids." Meanwhile, the number of U.S. deaths tied to drug overdoses fell last year for the first time in almost 30 years, according to the CDC.

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UC Davis begins study of new pain reliever in horses with chronic lameness

June 28, 2019 | UC Davis

A study is underway at the Center for Equine Health to evaluate a promising new pain reliever in horses with chronic lameness due to joint pain. This effort, led by Dr. Robert Brosnan, a professor in the School of Veterinary Medicine’s Department of Surgical and Radiological Sciences, is supported by a grant from the Equine Tribute and Memorial Fund through the Center for Equine Health. Dr. Brosnan and his team in the Department of Veterinary Anesthesiology and the JD Wheat Veterinary Orthopedic Research Laboratory are collaborating to evaluate a new painkiller that was discovered at the UC Davis School of Veterinary Medicine and compare its effectiveness with a standard treatment and a placebo in horses with chronic lameness.

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Task force calls for 'individualized, patient-centered approach' to pain management

May 30, 2019 | FierceHealthcare

Physicians treating patients with acute pain should focus on using a multimodal approach that includes medications, nerve blocks, physical therapy and other modalities, according to a federal task force's final report on acute and chronic pain management best practices (PDF) released Thursday. At the same time, doctors treating patients with chronic pain should look to a multidisciplinary approach across various fields. That could include medications, restorative therapies like physical therapy, cognitive therapies and complementary or integrative health.

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