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The last new inhaled anesthetic
was
discovered before we landed on the moon.

It's Time.

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Expanesthetics is being built by the anesthesia community.
Our next private investment offering is now open.*

We're developing a new generation of inhaled anesthetics designed to maintain hemodynamic stability.
Here's why over 100 clinicians have already joined us.

Read on
The Impact

The field is waking up to the risks of hypotension

A growing body of evidence suggests that intraoperative hypotension (IOH) may have a more significant impact on patient outcomes than previously recognized. Patient safety and regulatory agencies have begun to respond.

APSF
Anesthesia Patient Safety Foundation

The APSF published consensus recommendations on perioperative hemodynamic instability[1] and issued a public safety announcement on the risks of intraoperative hypotension.[2]

CMS
Centers for Medicare & Medicaid Services

Hypotension is the most common adverse event associated with surgeries and procedures according to a US government report,[3] and CMS has incorporated intraoperative hypotension into the MIPS reporting program as a marker of care quality.[4]

The Science

Three compounds that are normotensive at MAC

Our discovery platform has identified compounds that affect fewer unintended receptors and produce anesthesia while preserving hemodynamic stability in preclinical models[5], a profile no currently approved inhaled anesthetic can match.

65 75 85 95 105 EXP-GA-01 EXP-GA-12 EXP-GA-26 Halothane Isoflurane Sevoflurane MAP [mmHg] Mean Arterial Pressure at MAC for New Candidates vs Conventional Inhaled Anesthetics Data are represented as average +/- standard error. N=4 per drug. Results are compiled from multiple Expanesthetics studies.
The Community

Shaped by those who
practice it every day

Over 100 anesthesiologists and other anesthesia clinicians across the United States are building the future. Their continued backing reflects both confidence in the science and a belief that new anesthetic options can make a meaningful clinical and financial impact.

Map of 100+ clinician shareholders
Join Them

Will you help launch what's next?

Sign up to learn more about Expanesthetics and about our opportunity.*